Respiratory syncytial virus antibody test; RSV serology
RSV antibody test is a blood test that measures the levels of antibodies (immunoglobulins) that the body makes after an infection with the respiratory syncytial virus (RSV).
A blood sample is needed. For information on how this is done, see: Venipuncture.
There is no special preparation needed.
When the needle is inserted to draw blood, some people feel moderate pain, while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.
This test is done to identify someone who has been infected by RSV recently or in the past.
This test detects the virus itself. If the body has produced antibodies against RSV, then either a current or past infection has occurred.
In infants, RSV antibodies that have been passed from mother to baby may also be detected.
A negative test means the person does not have antibodies to RSV in the blood. This means the person has never had an RSV infection.
Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.
The examples above show the common measurements for results for these tests. Some laboratories use different measurements or may test different specimens.
A positive test means the person has antibodies to RSV in the blood. These antibodies may be present because:
There is very little risk involved with having your blood taken. Veins and arteries vary in size from one patient to another and from one side of the body to the other. Taking blood from some people may be more difficult than from others.
Other risks associated with having blood drawn are slight but may include:
This test is not much help because it does not detect RSV directly. It is not recommended in infants because the mother's antibodies may be detected. It is not useful in adults because most people have antibodies due to a past infection.
Breese HC. Respiratory syncytial virus. In: Mandell GL, Bennett JE, Dolin R, eds. Mandel, Douglas, and Bennett's Principles and Practice of Infectious Disease. 7th ed. Philadelphia, Pa: Saunders Elsevier; 2009:chap 158.
Walsh EE. Respiratory syncytial virus. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 385.
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