Definition of CSF myelin basic protein:

CSF myelin basic protein is a test to measure the level of myelin basic protein (MBP) in the cerebrospinal fluid (CSF), the clear liquid that surrounds the brain and spinal cord.

MBP is found in the material that covers many of your nerves.

How the test is performed:

A sample of spinal fluid is needed. For information on how this is done, see: Lumbar puncture

How the test will feel:

For detailed information, see the article on lumbar puncture.

Why the test is performed:

This test is done to see if myelin is breaking down. Multiple sclerosis is the most common cause for this, but other causes may include:

• Bleeding of the central nervous system
• Central nervous system trauma
• Certain brain diseases (encephalopathies)
• Infection of the central nervous system
• Stroke