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Chorionic villus sampling - Risks

What the risks are:

The risks of CVS are only slightly higher than those of an amniocentesis.

Possible complications include:

  • Bleeding
  • Infection
  • Miscarriage
  • Rh incompatibility in the mother
  • Rupture of membranes

Signs of complications include:

Report any signs of complications to your health care provider.

CVS may also cause limb problems in the fetus. This risk appears to be very low (1 in 3,000) when CVS is performed after 10 weeks gestational age.

Special considerations:

If your blood is Rh negative, you may receive RhoGAM to prevent Rh incompatibility.

You will receive a follow-up ultrasound 2 to 4 days after the procedure to make sure the pregnancy is proceeding normally.

  • Reviewed last on: 5/2/2008
  • Linda Vorvick, MD, Seattle Site Coordinator, Lecturer Maternal & Child Health, Pathophysiology, MEDEX Northwest Division of Physician Assistant Studies, University of Washington School of Medicine; and Susan Storck, MD, FACOG, Clinical Teaching Faculty, Department of Obstetrics and Gynecology, University of Washington School of Medicine; Chief, Eastside Department of Obstetrics and Gynecology, Group Health Cooperative of Puget Sound, Redmond, Washington. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Simpson JL. Otano L. Prenatal Genetic Diagnosis. In: Gabbe SG, Niebyl JR, Simpson JL. Obstetrics - Normal and Problem Pregnancies. 5th ed. New York, NY: Churchill Livingstone; 2007: Chap. 7.

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