Definition of Amylase - blood:

Amylase is an enzyme that helps digest carbohydrates. It is produced in the pancreas and the glands that make saliva. When the pancreas is diseased or inflamed, amylase releases into the blood.

A test can be done to measure the level of this enzyme in your blood.

Amylase may also be measured with a urine test. See amylase - urine.

How the test is performed:

A blood sample is needed. For information on how this is done, see: Venipuncture.

How to prepare for the test:

No special preparation is needed. However, you should avoid alcohol before the test. The health care provider may ask you to stop taking drugs that may affect the test. NEVER stop taking any medications without first talking to your doctor.

Drugs that can increase amylase measurements include:

• Asparaginase
• Aspirin
• Birth control pills
• Cholinergic medications
• Ethacrynic acid
• Methyldopa
• Opiates (codeine, meperidine, morphine)
• Thiazide diuretics

How the test will feel:

When the needle is inserted to draw blood, some people feel moderate pain, while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.

Why the test is performed:

This test is most often used to diagnose or monitor acute pancreatitis. It may also detect some digestive tract problems.

The test may also be done for the following conditions:

• Chronic pancreatitis
• Pancreatic pseudocyst