Definition of T-cell count:

T cells are a type of white blood cells (lymphocytes). They make up part of the immune system. T cells help the body fight diseases or harmful substances.

A test can be done to measure the number of T cells in your blood.

How the test is performed:

Blood is drawn from a vein, usually from the inside of the elbow or the back of the hand. The site is cleaned with germ-killing medicine (antiseptic). The health care provider wraps an elastic band around the upper arm to apply pressure to the area and make the vein swell with blood.

Next, the health care provider gently inserts a needle into the vein. The blood collects into an airtight vial or tube attached to the needle. The elastic band is removed from your arm.

Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.

In infants or young children, a sharp tool called a lancet may be used to puncture the skin and make it bleed. The blood collects into a small glass tube called a pipette, or onto a slide or test strip. A bandage may be placed over the area if there is any bleeding.

In the laboratory, the white blood cells (including T cells) are separated from the other blood cells. A stain or other substance that "labels" the cells is added to the sample to help identify which type of white blood cells are present.

How to prepare for the test:

No special preparation is necessary.

How the test will feel:

When the needle is inserted to draw blood, some people feel moderate pain, while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.

Why the test is performed:

Your doctor may order this test if you have signs of an immunodeficiency disorder or a disease of the lymph nodes. It is also used to monitor how well therapy for these types of diseases is working.