Definition of B-cell leukemia/lymphoma panel:

B-cell leukemia/lymphoma panel is a test that looks for certain proteins on the surface of white blood cells called B-lymphocytes. The proteins serve as markers that may be helpful in diagnosing leukemia or lymphoma.

How the test is performed:

A blood sample is needed. For information on how this is done, see: Venipuncture

Less commonly, white blood cells are removed during a bone marrow biopsy. The sample may also be taken during after a lymph node biopsy or other biopsy when lymphoma is suspected.

The blood sample is sent to a laboratory, where the specialist checks the cell type and characteristics. This procedure is called immunophenotyping. The test is usually done using a technique called flow cytometry.

How to prepare for the test:

No special preparation is usually necessary.

How the test will feel:

When the needle is inserted to draw blood, you may feel moderate pain, or only a prick or stinging sensation. Afterward, there may be some throbbing.

Why the test is performed:

This test may be performed:

• When other tests (such as a blood smear) indicate abnormal white blood cells
• When leukemia or lymphoma is suspected
• To determine the type of leukemia or lymphoma