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B lymphocyte cell surface markers
B-cell leukemia/lymphoma panel is a test that looks for certain proteins on the surface of white blood cells called B-lymphocytes. The proteins serve as markers that may be helpful in diagnosing leukemia or lymphoma.
A blood sample is needed. For information on how this is done, see: Venipuncture
The blood sample is sent to a laboratory, where the specialist checks the cell type and characteristics. This procedure is called immunophenotyping. The test is usually done using a technique called flow cytometry.
No special preparation is usually necessary.
When the needle is inserted to draw blood, you may feel moderate pain, or only a prick or stinging sensation. Afterward, there may be some throbbing.
This test may be performed:
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Bierman PJ, Harris N, Armitage JO. Non-Hodgkin's lymphomas. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 196.
Kantarjian H, O'Brien S. The chronic leukemias. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 195.
Najfeld V. Conventional and molecular cytogenetic basis of hematologic malignancies. In: Hoffman R, Benz EJ, Shattil SS, et al, eds. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 55.
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