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Histoplasma complement fixation - Results

Alternative Names

Histoplasma antibody test

Normal Values:

The absence of antibodies (negative test) is normal.

What abnormal results mean:

Abnormal results may mean you have an active histoplasmosis infection.

People who have been exposed to H. capsulatum in the past may also have antibodies to it, often at low levels. However, they may not have shown signs of illness.

Note: In the first stage of an illness, few antibodies may be detected. Antibody production increases during the course of an infection. For this reason, tests are often repeated several weeks after the first test.

  • Reviewed last on: 6/9/2011
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School, Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Kauffman CA. Histoplasmosis. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 353.

Deepe GS Jr. Histoplasma capsulatum. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2009:chap 264.

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