Anti-DNase B - Overview

Alternative Names

Antideoxyribonuclease B titer; ADN-B test

Definition of Anti-DNase B:

Anti-DNase B is a blood test to look for antibodies to a substance produced by Group A Streptococcus, the bacteria that cause strep throat.

How the test is performed:

A blood sample is needed. For information on how this is done, see: Venipuncture.

How to prepare for the test:

No special preparation is necessary.

How the test will feel:

When the needle is inserted to draw blood, some people feel moderate pain, while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.

Why the test is performed:

This test is most often done to tell if you have previously had a strep infection and if you might have rheumatic fever or kidney problems (glomerulonephritis) due to that infection.

Blood test

Reviewed last on: 6/9/2011
David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School, Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Bisno AL, Stevens DL. Streptococcus pyogenes. In: Mandell GL, Bennett JE, Dolin R, eds. Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2009:chap 198.

Stevens DL. Streptococcal infections. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 312.

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