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Histocompatibility antigen test - Results

Alternative Names

HLA typing; Tissue typing

Normal Values:

Each person has a small, relatively unique set of HLAs that they inherit from their parents. Children, on average, will have half of their HLAs match half of their mother's and half of their HLAs match half of their father's.

It is unlikely that two unrelated people will have the same HLA makeup, although identical twins may match each other.

Some HLA types are more common in certain autoimmune diseases. For example, HLA-B27 antigen is found in many people (but not all) with ankylosing spondylitis and Reiter syndrome.

  • Reviewed last on: 2/2/2011
  • Frank A. Greco, M.D., Ph.D., Director, Biophysical Laboratory, The Lahey Clinic, Burlington, MA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

References

Wang, E. Human Leukocyte Antigen and Human Neutrophil Antigen Systems. In: Hoffman R, Benz EJ, Shattil SS, et al, eds. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 145.
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