Serum leucine aminopeptidase
Leucine aminopeptidase is a protein, called an enzyme, that is normally found in liver cells and cells of the small intestine.
Serum leucine aminopeptidase is a test that measures how much of this protein is in your blood.
Your urine can also be checked for this protein. See: Leucine aminopeptidase - urine
A blood sample is needed. For information on how this is done, see: Venipuncture
Your health care provider may tell you to stop taking any drugs that could affect the test. Drugs that can affect the results of this test include estrogen and progesterone. Never stop taking any medicine without first talking to your doctor.
When the needle is inserted to draw blood, you may feel moderate pain, or only a prick or stinging sensation. Afterward, there may be some throbbing.
Your doctor may order this test to see if your liver is damaged. An excess of leucine aminopeptidase is released into your blood when your liver cells are damaged, or if you have a liver tumor.
This test is done only rarely, because other tests, such as gamma glutamyl transpeptidase are as accurate and are more easily available.
Berk P, Korenblatt K. Approach to the patient with jaundice or abnormal liver test results. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 150.
Pratt DS. Liver chemistry and function tests. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 9th ed. Philadelphia, Pa: Saunders Elsevier;2010:chap 73.
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