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Acetylcholine receptor antibody - Overview

Definition of Acetylcholine receptor antibody:

Acetylcholine receptor antibody is a substance found in the blood of people with myasthenia gravis. The antibody attacks receptors for a chemical called acetylcholine, which sends signals from nerves to muscles and between nerves in the brain.

How the test is performed:

Blood is drawn from a vein, usually from the inside of the elbow or the back of the hand. The site is cleaned with germ-killing medicine (antiseptic). The health care provider wraps an elastic band around the upper arm to apply pressure to the area and make the vein swell with blood.

Next, the health care provider gently inserts a needle into the vein. The blood collects into an airtight vial or tube attached to the needle. The elastic band is removed from your arm.

Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.

In infants or young children, a sharp tool called a lancet may be used to puncture the skin and make it bleed. The blood collects into a small glass tube called a pipette, or onto a slide or test strip. A bandage may be placed over the area if there is any bleeding.

How to prepare for the test:

No special preparation is required.

How the test will feel:

There may be a slight stinging or pricking sensation when blood is drawn, but this is usually mild and brief.

Why the test is performed:

This test is used to diagnose myasthenia gravis.

  • Reviewed last on: 5/25/2007
  • Daniel R Alexander, MD, Department of Internal Medicine, St. Mary's Hospital, Leonardtown, MD. Review provided by VeriMed Healthcare Network.
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