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Leukocyte esterase - Overview

Alternative Names

WBC esterase

Definition of Leukocyte esterase:

Leukocyte esterase is a urine test to look for white blood cells and other signs associated with infection.

How the test is performed:

A clean catch urine sample is needed. See: Urine specimen - clean catch

How to prepare for the test:

No special preparation is necessary for this test.

How the test will feel:

The test will involve only normal urination, and there is no discomfort.

Why the test is performed:

Leukocyte esterase is a screening test used to detect a substance that suggests there are white blood cells in the urine, which likely means a urinary tract infection.

This test is part of the routine urine dipstick test. If this test is positive, the urine should be examined under a microscope for white blood cells and other abnormalities associated with infection.

  • Reviewed last on: 8/28/2007
  • Daniel R Alexander, MD, Department of Internal Medicine, St. Mary's Hospital, Leonardtown, MD. Review provided by VeriMed Healthcare Network.