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Normal values are 60% to 150% inhibition.
A lack (deficiency) of protein C can lead to excess clotting. These clots tend to form in veins, not arteries.
Protein C deficiency can be either passed down through families (inherited) or it can develop with other conditions. Liver disease, disseminated intravascular coagulation (DIC), warfarin (Coumadin), chronic antibiotic use, and chemotherapy can cause low protein C levels.
Schafer A. Thrombotic disorders: Hypercoagulable states. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 182.