Sickledex; Hgb S test
“A blood sample is needed. For information on how this is done, see: Venipuncture
When the needle is inserted to draw blood, some people feel moderate pain, while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.
This test is done to tell if you have abnormal hemoglobin that causes sickle cell disease and sickle cell trait.
In sickle cell disease, a person has two abnormal hemoglobin S genes. A person with sickle cell trait has only one of these abnormal genes and no symptoms, or only mild ones.
This test does not tell the difference between these two conditions. Another test, called hemoglobin electrophoresis, will be done.
Saunthararajah Y, Vichinsky EP. Sickle cell disease – clinical features and management. In: Hoffman R, Benz EJ, Shattil SS, et al, eds. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 43.
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