Definition of DHEA-sulfate test:

DHEA-sulfate test measures the amount of DHEA-sulfate in the blood. DHEA-sulfate is a weak male hormone (androgen) produced by the adrenal gland in both men and women.

How the test is performed:

Blood is typically drawn from a vein, usually from the inside of the elbow or the back of the hand. The puncture site is cleaned with germ-killing medicine (antiseptic). The health care provider wraps an elastic band around the upper arm to apply pressure to the area and make the vein swell with blood.

Next, the health care provider gently inserts a needle into the vein. The blood collects into an airtight vial or tube attached to the needle. The elastic band is removed from your arm. Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.

In infants or young children, a sharp tool called a lancet may be used to puncture the skin and make it bleed. The blood collects into a small glass tube called a pipette, or onto a slide or test strip. A bandage may be placed over the area if there is any bleeding.

How to prepare for the test:

No special preparation is necessary. However, tell your health care provider if you are taking any vitamins or supplements that contain DHEA or DHEA-sulfate.

How the test will feel:

When the needle is inserted to draw blood, some people feel moderate pain, while others feel only a prick or sting. Afterward, there may be some throbbing.

Why the test is performed:

This test is done to check the function of the adrenal glands. The adrenal gland is one of the major sources of androgens in women.

The DHEA-sulfate test is often done in women who have male body characteristics (virilism) or excessive hair growth (hirsutism). It is also done in children who are maturing too early (precocious puberty).