Adrenal medullary imaging; Meta-iodobenzylguanidine scintiscan
An MIBG scintiscan is an imaging test that uses a radioactive substance (called a tracer) and a special scanner to find or confirm the presence of pheochromocytoma and neuroblastoma, which are tumors of specific types of nervous tissue.
See also: Nuclear scan
A radioisotope (MIBG, iodine-131-meta-iodobenzylguanidine) is injected into a vein. This compound attaches to specific tumor cells.
Later that day (or the next day) you lie on a table that is positioned under the arm of the scanner. The abdomen is scanned. You may be asked to return for repeated scans for 1 - 3 days. Each scan takes 1 - 2 hours.
Before or during the test, you may be given an iodine solution to prevent the thyroid from absorbing too much of the radioisotope.
You must sign an informed consent form. You will be asked to wear a hospital gown. However, loose-fitting clothing may be allowed. Remove jewelry or metal objects before each scan.
There is a sharp needle prick when the material is injected. The table may be cold or hard. You must lie still during the scan.
This test is done to confirm pheochromocytoma or neuroblastoma.
Aslam S, Sohaib A, Rockall A, Bomanji JB, Evanson J, Roznek RH. Imaging of the endocrine system. In: Adam A, Dixon AK, eds. Grainger & Allison's Diagnostic Radiology: A Textbook of Medical Imaging. 5th ed. New York, NY: Churchill Livingstone; 2008:chap 71.
Segerman D, Miles KA. Radionuclide imaging: general principles. In: Adam A, Dixon AK, eds. Grainger & Allison's Diagnostic Radiology: A Textbook of Medical Imaging. 5th ed. New York, NY: Churchill Livingstone; 2008:chap 7.
Young WF. Adrenal medulla, catecholamines, and pheochromocytoma. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 246.
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