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PPD skin test - Overview

Alternative Names

Purified protein derivative standard; TB skin test; Tuberculin skin test

Definition of PPD skin test:

The PPD skin test is a method used to diagnose tuberculosis. PPD stands for purified protein derivative.

How the test is performed:

The test site (usually the forearm) is cleansed. The PPD extract is then injected under the top layer of skin, causing a blister to form on the skin.

The reaction will take 48 - 72 hours to develop. You must return to your health care provider within that time to have the area checked. This will determine whether you have had a significant reaction to the PPD test. A reaction is measured in millimeters of hard swelling (induration) at the site.

How to prepare for the test:

There is no special preparation for this test.

Tell your health care provider if you have ever had a positive PPD skin test. If so, you should not have a repeat PPD test.

Tell your doctor if you have a medical condition or if you take certain drugs, such as steroids, that can affect your immune system. These situations may lead to inaccurate test results.

How the test will feel:

You will feel a brief sting as a needle is inserted just below the skin surface.

Why the test is performed:

The test is done to find out if you have been infected with tuberculosis.

  • Reviewed last on: 6/8/2007
  • Mark Levin, M.D., Division of Infectious Disease, MacNeal Hospital, Berwyn, IL. Review provided by VeriMed Healthcare Network.