Definition of Colposcopy - directed biopsy:

A colposcopy-directed biopsy uses a low-powered microscope called a colposcope to help view the surface of the cervix and show abnormalities.

How the test is performed:

You will lie on a table and place your feet in stirrups to position your pelvis for examination. The health care provider will insert an instrument (speculum) into your vagina to open the vaginal canal and examine the cervix.

The cervix is then swabbed with a chemical solution (acetic acid) to remove the mucus that covers the surface, and to highlight abnormal areas. The health care provider will place the colposcope at the opening of the vagina, and examine the area. Photographs may be taken.

If any areas look abnormal, a small sample of the tissue will be removed (biopsy) using small biopsy forceps. Many samples may be taken, depending on the size of the area.

How to prepare for the test:

There is no special preparation. You may be more comfortable if you empty your bladder and bowel before the procedure. You should not douche or have sexual intercourse for 24 hours before the exam.

How the test will feel:

A colposcopy is painless. Some women feel a slight sting from the vinegar solution. The biopsy may feel like a pinch each time a tissue sample is taken. You may have some cramping after the biopsy.

It is typical for women to hold their breath during pelvic procedures because they expect pain. Concentrating on slow, regular breathing will help you relax and help relieve pain.

Why the test is performed:

This procedure is usually done after a positive Pap smear to identify the abnormality.