Definition of Bone lesion biopsy:

A bone lesion biopsy is a test in which a piece of bone or bone marrow is removed for examination.

How the test is performed:

A bone lesion biopsy involves removal of a small piece of bone for examination. A special drill needle is usually used. A local anesthetic is given (to numb the area, the patient remains conscious), a small (about 1/8 inch) incision is made in the skin and the biopsy needle is pushed and twisted into the bone.

Once the sample is obtained, the needle is twisted out and the sample is sent for examination. Pressure is applied to the site. Once bleeding stops, the site is cleaned and covered with a bandage.

Bone biopsy may also be performed under general anesthesia for surgical excision (cutting out) of a piece of bone. Excision provides a larger specimen and may permit immediate surgical removal if examination indicates a malignant (cancerous) tumor.

How to prepare for the test:

You may be told not to drink or eat anything for several hours before the biopsy.

How the test will feel:

With a needle biopsy, you may feel moderate discomfort and pressure, even though a local anesthetic is used. You must remain still during the procedure.

After the biopsy, the area may be sore or tender for several days.

Why the test is performed:

The most common reasons for bone lesion biopsy are to tell the difference between cancerous and non-cancerous bone tumors and to identify other bone problem. It may be performed on people with bone pain and tenderness, particularly if x-ray, CT scan, or other testing reveals a problem.