Definition of Bone lesion biopsy:

A bone lesion biopsy is the removal of a piece of bone or bone marrow for examination.

How the test is performed:

The health care provider applies a numbing medicine (local anesthetic) to the area, and makes a small (about 1/8 inch) cut in the skin. A special drill needle is usually used. The biopsy needle is pushed and twisted into the bone.

Once the sample is obtained, the needle is twisted out and the sample is sent for examination. Pressure is applied to the site. Once bleeding stops, the site is cleaned and covered with a bandage.

Bone biopsy may also be done under general anesthesia to remove a larger sample. This may allow for immediate surgery to remove the bone if the exam shows that it is cancerous.

How to prepare for the test:

You may be told not to drink or eat anything for several hours before the biopsy.

How the test will feel:

With a needle biopsy, you may feel moderate discomfort and pressure, even though a local anesthetic is used. You must remain still during the procedure.

After the biopsy, the area may be sore or tender for several days.

Why the test is performed:

The most common reasons for bone lesion biopsy are to tell the difference between cancerous and noncancerous bone tumors and to identify other bone problem. It may be performed on people with bone pain and tenderness, particularly if x-ray, CT scan, or other testing reveals a problem.