Home Care:

As a general rule, your doctor should examine any skin rashes, including vesicles.

Over-the-counter treatments are available for certain conditions that cause vesicles, including poison ivy and cold sores.

Call your health care provider if:

Call your doctor if you have any unexplained blisters on your skin.

What to expect at your health care provider's office:

Your doctor will look at your skin. Some vesicules can be diagnosed simply by how they look.

In many cases, however, additional tests are needed. The fluid inside a blister may be sent to a lab for closer examination. In particularly difficult cases, a skin biopsy may be needed to make or confirm a diagnosis.