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Gestational trophoblastic disease (GTD) refers to a group of abnormalities in which tumors grow inside a woman's uterus (womb). The abnormal cells start in the tissue that would normally become the placenta, the organ that develops during pregnancy to feed the fetus.
A baby may or may not develop during these types of pregnancies.
There are several types of GTD. See the specific articles for more information:
Goldstein DP, Berkowitz RS. Gestational trophoblastic disease. In: Abeloff MD, Armitage JO, Niederhuber JE, Kastan MB, McKenna WG, eds. Abeloff’sClinical Oncology. 4th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 94.
Kavanagh JJ, Gershenson DM. Gestational Trophoblastic Disease: Hydatidiform Mole, Nonmetastatic and Metastatic Gestational Trophoblastic Tumor: Diagnosis and Management. In: Katz VL, Lentz GM, Lobo RA, Gershenson DM. Comprehensive Gynecology. 5th ed. Philadelphia, Pa: Mosby Elsevier; 2007:chap 35.
Soper J, Creasman JT. Gestational trophoblastic disease. In: Disaia PJ, Creasman WT, eds. Clinical Gynecologic Oncology. 7th ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 7.
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