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Histoplasmosis pulmonar aguda (primaria) - Symptom

Síntomas:

La mayoría de las personas con histoplasmosis no presentan síntomas o sólo síntomas leves. Los síntomas más comunes son:

  • Dolor torácico
  • Escalofrío
  • Tos
  • Fiebre
  • Dolor y rigidez articular
  • Dolores y rigidez muscular
  • Salpullido (generalmente pequeñas úlceras en la parte inferior de las piernas llamadas eritema nodoso)
  • Dificultad para respirar

En las personas muy jóvenes, de edad avanzada o inmunocomprometidas, los síntomas pueden ser más graves, como:

  • Inflamación alrededor del corazón (llamada pericarditis)
  • Infecciones pulmonares graves
  • Dolor articular intenso

Signos y exámenes:

Para diagnosticar la histoplasmosis, un médico necesita encontrar el hongo en el cuerpo o evidencia de que el sistema inmunitario está reaccionando a dicho hongo.

Los exámenes abarcan:

  • Pruebas de anticuerpos para histoplasmosis (también llamadas serologías)
  • Biopsia del sitio de la infección
  • Broncoscopia (generalmente realizada sólo si los síntomas son graves o si la persona tiene un sistema inmunitario anormal)
  • Conteo sanguíneo completo (CSC) con fórmula leucocitaria
  • Tomografía computarizada del tórax
  • Radiografía de tórax (podría mostrar infección pulmonar o neumonía)
  • Cultivo de esputo (frecuentemente no positivo, incluso si usted está infectado)
  • Antígeno de Histoplasma capsulatum en orina (más útil en personas con enfermedad grave)
  • Reviewed last on: 5/25/2010
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School, Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Kauffman CA. Histoplasmosis. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, PA: Saunders Elsevier; 2007:chap 353.

Waht LJ, Freifeld AG, Kleiman MB, et al. Clinical practice guidelines for the management of patients with histoplasmosis: 2007 update by the Infectious Diseases Society of America. Clin Infect Dis. 2007;45(7):807-825.

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