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Síndrome de Caplan - Overview

Nombres alternativos

Neumoconiosis reumatoidea

Definición:

Es la hinchazón (inflamación) y cicatrización de los pulmones en personas con artritis reumatoidea que han estado expuestas al polvo de las minas que contienen carbón. La enfermedad pulmonar se denomina neumoconiosis de los mineros del carbón.

Causas:

El síndrome de Caplan es causado por la inhalación de polvo de las minas del carbón, lo cual causa inflamación y puede llevar al desarrollo de muchas protuberancias (nódulos) pulmonares pequeñas y a una enfermedad leve de las vías respiratorias similar al asma.

Algunas personas que han estado expuestas al polvo presentan una cicatrización pulmonar severa, llamada fibrosis masiva y progresiva, que le dificulta a los pulmones el transporte de oxígeno al torrente sanguíneo. Las personas con artritis reumatoidea no parecen tener una mayor probabilidad de presentar esta complicación de la cicatrización.

El síndrome de Caplan es muy poco común en los Estados Unidos.

Sistema respiratorio

Reviewed last on: 6/10/2011
David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Denis Hadjiliadis, MD, Assistant Professor of Medicine, Division of Pulmonary, Allergy and Critical Care, University of Pennsylvania, Philadelphia, PA. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Corte TJ, duBois RM. The lungs and connective tissue diseases. In: Mason RJ, Broaddus VC, Martin TR, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine. 5th ed. Philadelphia, Pa: Saunders Elsevier; 2010:chap 58.

Cowie RL, Murray J, Becklake MR. Pneumoconioses and other mineral dust-related diseases. In: Mason RJ, Broaddus VC, Martin TR, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine. 5th ed. Philadelphia, Pa: Saunders Elsevier; 2010:chap 65.

Raghu G. Interstitial lung disease. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 92.

Samet JM. Occupational pulmonary disorders. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap93.

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