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Enfermedad de Whipple - Treatment

Nombres alternativos

Lipodistrofia intestinal

Tratamiento:

Las personas con la enfermedad de Whipple necesitan tomar antibióticos por tiempo prolongado para curar cualquier infección del sistema nervioso central y del cerebro. Se administra un antibiótico llamado ceftriaxona a través una vena (IV), seguido de otro antibiótico, como trimetoprima con sulfametoxazol, que se toma por vía oral hasta por un año.

Si los síntomas reaparecen durante la terapia con antibióticos, el tratamiento se puede cambiar.

El médico le debe hacer un seguimiento minucioso a su progreso, debido a que los signos de la enfermedad pueden reaparecer después de que usted termine la terapia. Asimismo, las personas con deficiencias nutricionales a causa de la malabsorción necesitarán tomar suplementos dietéticos.

Expectativas (pronóstico):

Sin tratamiento, la enfermedad con frecuencia es mortal. El tratamiento alivia los síntomas y puede curar la enfermedad.

Complicaciones:

  • Daño cerebral
  • Daño a las válvulas cardíacas (por endocarditis)
  • Deficiencias nutricionales
  • Reaparición de los síntomas (lo cual puede darse debido a la resistencia al medicamento)
  • Pérdida de peso

Situaciones que requieren asistencia médica:

Consulte con el médico si se presenta dolor articular, dolor abdominal o diarrea persistentes.

Si está recibiendo tratamiento para la enfermedad de Whipple, consulte con el médico si:

  • Los síntomas empeoran o no mejoran
  • Los síntomas reaparecen
  • Se presentan nuevos síntomas
  • Reviewed last on: 5/4/2010
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; George F. Longstreth, MD, Department of Gastroenterology, Kaiser Permanente Medical Care Program, San Diego, CA. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

West SG. Systemic diseases in which arthritis is a feature. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 297.

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