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Colestasis inducida por medicamentos - Treatment

Nombres alternativos

Colestasis inducida por fármacos

Tratamiento:

Si el medicamento está causando la colestasis, es probable que el médico le ordene suspenderlo y le recetará un medicamento alternativo, de ser posible. NO suspenda medicamentos por su cuenta sin consultarlo con el médico. No existe ningún medicamento para neutralizar la colestasis inducida por fármacos.

La colestiramina (o colestipol) puede reducir la picazón.

La terapia sustitutiva de vitaminas repone las vitaminas A, K y D, que se pierden en las deposiciones grasosas. Se debe agregar un suplemento de calcio para prevenir o tratar los huesos blandos y débiles (osteomalacia).

Expectativas (pronóstico):

La mayoría de los pacientes se recupera, pero los casos graves pueden llevar a que se presente insuficiencia hepática. La colestasis inducida por medicamentos generalmente se contrarresta después de que usted deja de tomar el medicamento o fármaco; sin embargo, puede tomar muchos meses para que la colestasis mejore.

Complicaciones:

Diarrea
Absorción deficiente de grasas y vitaminas liposolubles
Picazón intensa

Situaciones que requieren asistencia médica:

Consulte con el médico si presenta picazón persistente o si nota una coloración amarillenta en ojos y piel.

Trayecto de la bilis

Reviewed last on: 5/4/2010
David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; George F. Longstreth, MD, Department of Gastroenterology, Kaiser Permanente Medical Care Program, San Diego, CA. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Afdhal NH. Diseases of the gall bladder and bile ducts. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 159.

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