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Hiperlipidemia combinada familiar - Overview

Nombres alternativos

Hiperlipidemia tipo lipoproteína múltiple

Definición:

Es un trastorno de niveles de colesterol y triglicéridos altos en la sangre que se hereda, lo cual significa que se transmite de padres a hijos.

Causas, incidencia y factores de riesgo:

La hiperlipidemia combinada familiar es el trastorno genético más común de aumento de grasas en la sangre que causa ataques cardíacos precoces. Sin embargo, los investigadores aún no han identificado los genes específicos responsables.

La diabetes, el alcoholismo y el hipotiroidismo empeoran esta afección. Los factores de riesgo abarcan antecedentes familiares de colesterol alto y arteriopatía coronaria temprana.

  • Reviewed last on: 5/23/2010
  • David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc., and David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine.

Referencias

Genest J, Libby P. Lipoprotein disorders and cardiovascular disease In: Libby P, Bonow RO, Mann DL, Zipes DP, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 8th ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 42.

Mahley RW, Weisgraber KH, Bersot TP. Disorders of lipid metabolism. In: Kronenberg HM, Melmed S, Polonsky KS, Larsen PR, eds. Williams Textbook of Endocrinology. 11th ed. Philadelphia, Pa: Saunders Elsevier; 2008:chap 36.

Semenkovich CF. Disorders of lipid metabolism. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 217.

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