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Disbetalipoproteinemia familiar
Definición:
Es un trastorno transmitido de padres a hijos por el cual hay altas cantidades de colesterol y triglicéridos en la sangre.
Nombres alternativos:
Hiperlipoproteinemia tipo III; ApolipoproteÃna E deficiente o defectuosa
Causas, incidencia y factores de riesgo:
La afección es causada por un defecto en los genes que provoca una acumulación de grandes partÃculas de lipoproteÃna que contienen colesterol y triglicéridos. Esta enfermedad está ligada a defectos en el gen para la alipoproteÃna E en muchas casos.
La afección incrementa el riesgo de una persona a padecer arteriopatÃa coronaria y enfermedad vascular periférica.
El hipotiroidismo , la obesidad o la diabetes pueden hacer empeorar la enfermedad. Los factores de riesgo comprenden los antecedentes familiares de disbetalipoproteinemia familiar o una arteriopatÃa coronaria.
- Fecha de revisión: 5/16/2007
- Versión en inglés revisada por: Brian Kirmse, MD, Mount Sinai School of Medicine, Department of Human Genetics, New York, NY. Review provided by VeriMed Healthcare Network.
- Traducción y localización realizada por: DrTango, Inc.
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