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Síndrome de Cushing debido a un tumor suprarrenal - Treatment

Nombres alternativos

Síndrome de Cushing por tumor suprarrenal

Tratamiento:

El síndrome de Cushing debido a un tumor suprarrenal se trata mediante la extirpación quirúrgica del tumor y con frecuencia de toda la glándula suprarrenal.

Usualmente se requiere terapia de reemplazo con glucocorticoides, posiblemente durante un período de 9 a 12 meses, hasta que la otra glándula suprarrenal se recupere de la cirugía.

Si la cirugía no es posible, como en los casos de cáncer suprarrenal, se pueden utilizar medicamentos para detener la secreción de cortisol, como:

  • Aminoglutetimida
  • Ketoconazol
  • Mifepristona
  • Mitotano

La radioterapia generalmente no funciona para los tumores suprarrenales cancerosos y no es apropiada para los tumores no cancerosos.

Pronóstico:

El pronóstico para pacientes con tumor suprarrenal que se someten a cirugía es excelente; de hecho, las tasas de efectividad de dicha cirugía son muy altas con este tipo de tumor.

En caso de cáncer suprarrenal, la cirugía algunas veces no es posible, y cuando se practica no siempre cura el cáncer.

Posibles complicaciones:

Los tumores suprarrenales cancerosos se pueden diseminar al hígado o a los pulmones.

Cuándo contactar a un profesional médico:

Consulte con el médico si desarrolla alguno de los síntomas del síndrome de Cushing.

  • Reviewed last on: 11/23/2009
  • Ari S. Eckman, MD, Division of Endocrinology and Metabolism, Johns Hopkins School of Medicine, Baltimore, MD. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Stewart PM. The adrenal cortex. In: Kronenberg HM, Melmed S, Polonsky KS, Larsen PR. Williams Textbook of Endocrinology. 11th ed. Philadelphia, PA: Elsevier; 2008:chap 14.

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