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Síndrome de Cushing - Symptom

Nombres alternativos

Hipercortisolismo

Síntomas:

La mayoría de las personas con el síndrome de Cushing tendrá:

  • Obesidad en la parte superior del cuerpo (por encima de la cintura) y brazos y piernas delgados
  • Cara redonda, roja y llena (cara de luna llena)
  • Tasa de crecimiento lenta en niños

Cambios de piel que se ven con frecuencia:

  • Acné o infecciones de la piel
  • Marcas purpúreas (½ pulgada o más de ancho) llamadas estrías en la piel del abdomen, los muslos y las mamas
  • Piel delgada con propensión a los hematomas

Los cambios musculares y óseos abarcan:

  • Dolor de espalda que ocurre con las actividades rutinarias
  • Dolor o sensibilidad en los huesos
  • Acumulación de grasa entre los hombros (joroba de búfalo)
  • Adelgazamiento de los huesos, lo cual lleva a fracturas de costillas y columna vertebral
  • Músculos débiles

Las mujeres con el síndrome de Cushing con frecuencia tienen:

Los hombres pueden tener:

  • Disminución de la fertilidad
  • Disminución o ausencia de deseo sexual
  • Impotencia

Otros síntomas que pueden ocurrir con esta enfermedad:

Pruebas y exámenes:

La glucemia y los conteos de glóbulos blancos pueden estar altos. El nivel de potasio puede estar bajo.

Los exámenes de laboratorio que se pueden hacer para diagnosticar el síndrome de Cushing e identificar la causa son:

Los exámenes para determinar la causa o complicaciones pueden abarcar:

También puede presentarse colesterol alto, incluyendo triglicéridos altos y bajo nivel de lipoproteína de alta densidad (HDL).

  • Reviewed last on: 10/14/2009
  • Ari S. Eckman, MD, Division of Endocrinology and Metabolism, Johns Hopkins School of Medicine, Baltimore, MD. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Stewart PM. The adrenal cortex. In: Kronenberg HM, Shlomo M, Polonsky KS, Larsen PR, eds. Williams Textbook of Endocrinology. 11th ed. Philadelphia, Pa: Saunders Elsevier;2008:chap 14.

Carroll T, Raff H, Findling JW. Late-night salivary control measurement in the diagnosis of Cushing's syndrome. Nat Clin Pract Endocrinol Metab. 2008;4:344-350.

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