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Síndrome de Cushing - Treatment

Nombres alternativos

Hipercortisolismo

Tratamiento:

El tratamiento depende de la causa.

Síndrome de Cushing causado por el uso de corticosteroides:

  • Disminuir lentamente la dosis del fármaco (si es posible) bajo supervisión médica.
  • Si no se puede dejar de tomar el medicamento debido a la enfermedad, se debe vigilar con cuidado el azúcar alto en la sangre, los niveles altos de colesterol y el adelgazamiento de los huesos u osteoporosis.

Síndrome de Cushing causado por un tumor hipofisario o un tumor que segregue corticotropina:

  • Cirugía para extirpar el tumor
  • Radiación después de la extirpación de un tumor hipofisario (en algunos casos)
  • Se puede necesitar terapia de reemplazo con hidrocortisona (cortisol) después de la cirugía y, posiblemente, continuarla durante toda la vida

Síndrome de Cushing debido a un tumor suprarrenal u otros tumores:

  • Cirugía para extirpar el tumor
  • Si el tumor no se puede extirpar, medicamentos para ayudar a bloquear la secreción de cortisol

Pronóstico:

La extirpación del tumor puede conducir a una recuperación total, pero existe la probabilidad de que la afección reaparezca.

La supervivencia de personas con tumores ectópicos depende del tipo de tumor. Sin tratamiento, el síndrome de Cushing es potencialmente mortal.

Posibles complicaciones:

Cuándo contactar a un profesional médico:

Consulte con el médico si tiene síntomas del síndrome de Cushing.

  • Reviewed last on: 10/14/2009
  • Ari S. Eckman, MD, Division of Endocrinology and Metabolism, Johns Hopkins School of Medicine, Baltimore, MD. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Stewart PM. The adrenal cortex. In: Kronenberg HM, Shlomo M, Polonsky KS, Larsen PR, eds. Williams Textbook of Endocrinology. 11th ed. Philadelphia, Pa: Saunders Elsevier;2008:chap 14.

Carroll T, Raff H, Findling JW. Late-night salivary control measurement in the diagnosis of Cushing's syndrome. Nat Clin Pract Endocrinol Metab. 2008;4:344-350.

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