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Enfermedad ósea de Paget - Overview

Nombres alternativos

Osteítis deformante

Definición:

La enfermedad de Paget es un trastorno que involucra destrucción y regeneración anormal del hueso, lo cual causa deformidad.

Causas:

No se conoce la causa de la enfermedad de Paget, aunque podría tener que ver con los genes o una infección viral temprana en la vida.

La enfermedad se presenta a nivel mundial, pero es más común en Europa, Australia y Nueva Zelanda.

En las personas que padecen esta enfermedad, hay una descomposición anormal del tejido óseo, seguida por una formación ósea anormal. El nuevo hueso es más grande, pero débil y lleno de vasos sanguíneos nuevos.

La enfermedad se puede localizar únicamente en una o en dos áreas del esqueleto o en todo el cuerpo. A menudo, compromete huesos de:

  • El brazo
  • La clavícula
  • La pierna
  • La pelvis
  • La columna
  • Reviewed last on: 11/23/2009
  • Ari S. Eckman, MD. Division of Endocrinology and Metabolism, Johns Hopkins School of Medicine, Baltimore, MD. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M. Inc.

Referencias

Goldman L, Ausiello D. Cecil Textbook of Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007.
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