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Síndrome de Sjögren - Overview

Nombres alternativos

Xerostomía-Síndrome de Sjögren; Queratoconjuntivitis seca-Síndrome de Sjögren; Síndrome seco (o de las mucosas secas)

Definición:

Es un trastorno autoinmunitario en el cual se destruyen las glándulas que producen las lágrimas y la saliva, causando resequedad en la boca y en los ojos. Sin embargo, este trastorno puede afectar muchas partes diferentes del cuerpo, entre ellas, los riñones y los pulmones.

Causas:

Se desconoce la causa del síndrome de Sjögren. Es un trastorno autoinmunitario, lo cual significa que el cuerpo ataca por error al tejido sano. El síndrome ocurre con mayor frecuencia en mujeres de 40 a 50 años y es poco frecuente en niños.

El síndrome de Sjögren primario se define como resequedad en ojos y boca sin otro trastorno autoinmunitario.

El síndrome de Sjögren secundario ocurre solo con otro trastorno autoinmunitario como:

Este síndrome afecta aproximadamente de 1 a 4 millones de personas en los Estados Unidos.

Anticuerpos

Reviewed last on: 6/28/2011
Ariel D. Teitel, M.D., M.B.A., Chief, Division of Rheumatology, St. Vincent’s Hospital, New York, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Kruszka P, O'Brian RJ. Diagnosis and management of Sjogren syndrome. Am Fam Physician. 2009;79:465-470.

Wu AJ. Optimizing dry mouth treatment for individuals with Sjögren's syndrome. Rheum Dis Clin North Am. 2008 Nov;34(4):1001-10, x.

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