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Acidosis tubular renal distal - Overview

Nombres alternativos

Acidosis tubular renal tipo I; Acidosis tubular distal renal; ATR tipo I; ATR distal; ATR clásica

Definición:

Es una enfermedad que ocurre cuando los riñones no eliminan el ácido apropiadamente en la orina, dejando la sangre demasiado ácida (llamada acidosis).

Causas, incidencia y factores de riesgo:

Los riñones regulan el pH del cuerpo removiendo los ácidos de la sangre y eliminándolos en la orina.

La acidosis tubular renal distal (ATR tipo I) es causada por un defecto en los conductos renales que provoca que el ácido se acumule en el torrente sanguíneo.

La ATR Tipo I es causada por una variedad de afecciones, incluyendo:

  • Amiloidosis
  • Enfermedad de Fabry
  • Enfermedad drepanocítica
  • Síndrome de Sjögren
  • Lupus eritematoso sistémico
  • Enfermedad de Wilson
  • Uso de ciertos fármacos como anfotericina B, litio y analgésicos
  • Reviewed last on: 11/30/2009
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Herbert Y. Lin, MD, PHD, Nephrologist, Massachusetts General Hospital; Associate Professor of Medicine, Harvard Medical School. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Seifter JL. Acid-base disorders. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 119.

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