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Enfermedad con cambios mínimos - Overview

Nombres alternativos

Síndrome nefrótico con cambio mínimo; Enfermedad de Nil; Nefrosis lipoide; Síndrome nefrótico idiopático de la niñez

Definición:

Es un trastorno renal que puede llevar a síndrome nefrótico, aunque las nefronas del riñón lucen normales bajo un microscopio regular.

Causas, incidencia y factores de riesgo:

Cada riñón está compuesto de más de un millón de unidades llamadas nefronas, las cuales filtran la sangre y producen la orina.

En la enfermedad con cambios mínimos, hay un daño a los glomérulos, los pequeños vasos sanguíneos dentro de la nefrona. La enfermedad recibe su nombre debido a que este daño no es visible bajo un microscopio regular y sólo se puede observar con un microscopio electrónico.

La enfermedad con cambios mínimos es la causa más común de síndrome nefrótico en niños y también se observa en adultos.

La causa se desconoce, pero la enfermedad puede ocurrir después de:

  • Reacciones alérgicas
  • Vacunas recientes
  • Infección viral
  • Reviewed last on: 11/30/2009
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Herbert Y. Lin, MD, PHD, Nephrologist, Massachusetts General Hospital; Associate Professor of Medicine, Harvard Medical School. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Appel GB. Glomerular disorders and nephrotic syndromes. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 122.

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