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Contenido en el Idioma Español de University of Maryland Medical Center

Hemofilia - Overview

Definición:

Se refiere a un grupo de trastornos hemorrágicos en los cuales la sangre tarda mucho tiempo para coagularse.

Temas relacionados:

Causas:

Cuando uno sangra, el cuerpo inicia una serie de reacciones que ayudan a coagular la sangre, lo cual se denomina cascada de la coagulación. El proceso involucra a proteínas especiales llamadas factores de coagulación. Cuando falta uno o más de estos factores de coagulación, generalmente hay una posibilidad más alta de sangrado.

La hemofilia es causada por una falta de suficiente factor VIII o IX. En la mayoría de los casos, la hemofilia se transmite de padres a hijos (hereditaria) y afecta con mayor frecuencia a los hombres.

Coágulos sanguíneos

Reviewed last on: 2/28/2011
David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Kessler C. Hemorrhagic disorders: Coagulation factor deficiencies. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 180.

Ragni MV, Kessler CM, Lozier JN. Clinical aspects and therapy for hemophilia. In: Hoffman R, Benz EJ Jr, Shattil SJ, et al, eds. Hoffman Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Churchill Livingstone Elsevier;2008:chap 2005.

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