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Fibrinólisis primaria o secundaria - Overview

Nombres alternativos

Fibrinólisis

Definición:

Es un proceso corporal normal que impide que los coágulos sanguíneos que ocurren en forma natural crezcan y causen problemas.

La fibrinólisis primaria se refiere a la descomposición normal de los coágulos, mientras que la fibrinólisis secundaria es la descomposición de los coágulos sanguíneos debido a un trastorno médico, un medicamento u otra causa.

Causas, incidencia y factores de riesgo:

Los coágulos de sangre se forman a partir de una proteína llamada fibrina. La descomposición de la fibrina (fibrinólisis) puede incrementarse bajo ciertas condiciones, tales como:

Infecciones bacterianas
Ejercicio intenso
Glucemia baja
Oxigenación insuficiente a los tejidos

En algunas situaciones, es posible que los médicos quieran acelerar el proceso de fibrinólisis. Por ejemplo, cuando se forma un coágulo anormal en los vasos sanguíneos del corazón y provoca un ataque cardíaco, se pueden suministrar sustancias fibrinolíticas sintéticas (como tPA, estreptocinasa o Retavase) para disolverlo.

Formación de coágulos sanguíneos

Coágulos sanguíneos

Reviewed last on: 2/5/2010
David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Schafer AI. Hemorrhagic disorders: Disseminated intravascular coagulation, liver failure, and vitamin K deficiency. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 181.

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