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Anemia hemolítica autoinmunitaria idiopática - Overview

Nombres alternativos

Anemia hemolítica idiopática autoinmunitaria; Anemia hemolítica autoinmunológica

Definición:

Es una disminución en el número de glóbulos rojos debido a un incremento de su destrucción por parte del sistema de defensas (inmunitario) del cuerpo.

Causas, incidencia y factores de riesgo:

La anemia hemolítica autoinmunitaria idiopática es una enfermedad adquirida que ocurre cuando se forman anticuerpos contra los propios glóbulos rojos de una persona. En la forma idiopática de esta enfermedad, se desconoce la causa.

Este tipo de anemia representa la mitad de todas las anemias hemolíticas inmunitarias.

Existen otros tipos de anemias hemolíticas inmunitarias cuyas causas pueden ser el resultado de una enfermedad subyacente o de medicamentos. La enfermedad puede comenzar muy rápidamente y ser muy seria.

Se desconocen los factores de riesgo.

Anticuerpos

Reviewed last on: 1/31/2010
Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington, School of Medicine; and Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Schwartz RS. Autoimmune and intravascular hemolytic anemias. In: Goldman L, Ausiello D. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 164.

Powers A, Silberstein LE. Autoimmune hemolytic anemia. In: Hoffman R, Benz EJ, Shattil SS, et al., eds. Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 47.

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