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Mieloma múltiple - Overview

Nombres alternativos

Plasmacitoma maligno; Plasmacitoma del hueso; Mieloma de células plasmáticas; Discrasia de células plasmáticas

Definición:

Es un cáncer de las células plasmáticas en la médula ósea.

Causas:

Las células plasmáticas ayudan al cuerpo a combatir la enfermedad produciendo proteínas llamadas anticuerpos. En el mieloma múltiple, las células plasmáticas crecen fuera de control en la médula ósea y forman tumores en áreas de hueso sólido.

La proliferación excesiva de estos tumores óseos hace que sea más difícil para la médula producir plaquetas y glóbulos sanguíneos saludables.

El mieloma múltiple afecta principalmente a los adultos mayores. Un tratamiento pasado de radioterapia aumenta el riesgo de sufrir este tipo de cáncer.

  • Reviewed last on: 2/28/2011
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

National Comprehensive Cancer Network. National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology: Multiple Myeloma. 2011. Version 1.2011. Accessed January 29, 2011.

Rajkumar SV, Dispenzieri A. Multiple myeloma and related disorders. In: Abeloff MD, Armitage JO, Niederhuber JE, Kastan MB, McKenna WG, eds. Abeloff’s Clinical Oncology. 4th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 110.

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