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Macroglobulinemia de Waldenstrom
Nombres alternativos:
Macroglobulinemia primaria; Linfoma linfoplasmacÃtico
Tratamiento:
La plasmaféresis o intercambio de plasma elimina sustancias indeseables de la sangre. En la macroglobulinemia, este procedimiento elimina o reduce el alto nivel de IgM y se utiliza para controlar rápidamente los sÃntomas causados por el espesamiento de la sangre.
La terapia con medicamentos puede incluir esteroides, Leukeran, Alkeran, Citoxan, fludarabina o rituximab.
Los pacientes con un bajo número de glóbulos rojos, de glóbulos blancos o de plaquetas pueden requerir transfusiones o antibióticos.
Expectativas (pronóstico):
La supervivencia promedio es de alrededor de cinco años. En algunas personas, el trastorno puede producir pocos sÃntomas y progresar lentamente.
Complicaciones:
- Problemas de la visión
- Sangrado gastrointestinal
- Cambios en el funcionamiento mental, que posiblemente lleven a coma
- Insuficiencia cardÃaca congestiva
Situaciones que requieren asistencia médica:
Se debe buscar asistencia médica si se desarrollan sÃntomas de este trastorno.
Referencias:
Ferri FF. Ferri’s Clinical Advisor: Instant Diagnosis and Treatment. 8th ed. St. Louis, Mo: Mosby; 2006:909.
Goldman L, Ausiello D. Cecil Textbook of Medicine. 22nd ed. Philadelphia, Pa: WB Saunders; 200:1068, 1992.
- Fecha de revisión: 9/20/2006
- Versión en inglés revisada por: Corey Cutler, MD, MPH, FRCP(C), Assistant Professor of Medicine, Harvard Medical School; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA. Review provided by VeriMed Healthcare Network.
- Traducción y localización realizada por: DrTango, Inc.
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