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Sarcoma de Kaposi - Overview

Definición:

Es un tumor canceroso del tejido conectivo, a menudo asociado con el SIDA.

Causas, incidencia y factores de riesgo:

Antes de la epidemia del SIDA, el sarcoma de Kaposi se presentaba principalmente en hombres mayores italianos y judíos, y rara vez, en mujeres de edad avanzada. Entre este grupo, los tumores se desarrollaban lentamente. En los pacientes con SIDA, el cáncer se puede desarrollar rápidamente y también puede comprometer la piel, los pulmones, el tubo digestivo y otros órganos.

En personas con SIDA, el sarcoma de Kaposi es causado por una interacción entre el VIH, un sistema inmunitario debilitado y el herpes virus humano 8 (HHV-8). El sarcoma de Kaposi ha estado vinculado a la diseminación del VIH y el HHV-8 a través de la actividad sexual.

Las personas que se someten a trasplantes de riñón o a otros trasplantes de órganos también están en riesgo de padecer el sarcoma de Kaposi.

El sarcoma de Kaposi africano es bastante común en hombres adultos jóvenes que viven cerca del ecuador. Una forma de esta enfermedad también es común en niños pequeños africanos.

  • Reviewed last on: 9/15/2010
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Volberding PA. Hematology and oncology in patients with human immunodeficiency virus infection. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 416.

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