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Leucoencefalopatía multifocal progresiva - Overview

Nombres alternativos

LEMP

Definición:

Es un trastorno raro que ocasiona daño al material (mielina) que cubre y protege los nervios en la sustancia blanca del cerebro.

Causas, incidencia y factores de riesgo:

El virus JC (VJC) causa la leucoencefalopatía multifocal progresiva (LEMP). Hacia la edad de 10 años, la mayoría de las personas han estado infectadas, pero casi nunca provoca síntomas.

Sin embargo, cualquier persona con un sistema inmunitario debilitado está en mayor riesgo de desarrollar LEMP. Las causas para que se presente un sistema inmunitario debilitado abarcan:

SIDA (menos común ahora debido a los mejores tratamientos para esta enfermedad)
Ciertos medicamentos empleados para tratar la esclerosis múltiple, la artritis reumatoidea y enfermedades conexas
Leucemia y linfoma

Materia gris y blanca del cerebro

Leucoencefalopatía

Reviewed last on: 2/6/2010
David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Luc Jasmin, MD, PhD, Department of Neurosurgery at Cedars-Sinai Medical Center, Los Angeles, CA, and Department of Anatomy at UCSF, San Francisco, CA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Boren EJ, Cheema GS, et al. The emergence of progressive multifocal leukoencephaloparhy (PML) in rheumatic diseases. J Autoimmun. 2008;30(1-2):90-98.

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