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Rechazo al trasplante - Treatment

Nombres alternativos

Rechazo al injerto; Rechazo a un órgano o tejido

Tratamiento:

El objetivo del tratamiento es verificar que el órgano o tejido transplantado funcione apropiadamente e inhibir la respuesta inmunitaria. La inhibición de la respuesta inmunitaria puede prevenir el rechazo al trasplante.

Se pueden utilizar muchos fármacos diferentes para inhibir la respuesta inmunitaria. La dosificación del medicamento depende de su estado. La dosis puede ser muy alta mientras el tejido realmente esté siendo rechazado y luego se puede reducir para evitar que el rechazo suceda de nuevo.

Pronóstico:

Algunos órganos y tejidos son trasplantados con mayor éxito que otros. Si se presenta el rechazo, los medicamentos inmunodepresores pueden detenerlo. Entonces, usted deberá tomar dichos medicamentos por el resto de su vida.

Sin embargo, el tratamiento inmunodepresor no siempre tiene éxito.

Posibles complicaciones:

  • Ciertos cánceres (en algunas personas que toman fármacos inmunodepresores fuertes durante mucho tiempo).
  • Infecciones (debido a la inhibición del sistema inmunitario de la persona).
  • Pérdida de funcionamiento del órgano/tejido trasplantado.
  • Efectos secundarios de los medicamentos, que pueden ser graves.

Cuándo contactar a un profesional médico:

Consulte con el médico si el órgano o tejido trasplantado no parece estar trabajando apropiadamente o si aparecen otros síntomas. También, llame al médico si se desarrollan efectos secundarios por los medicamentos.

  • Reviewed last on: 6/14/2011
  • Shabir Bhimji, MD, PhD, Specializing in General Surgery, Cardiothoracic and Vascular Surgery, Midland, TX. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Eghtesad B, Miller CM, Fung JJ. Liver transplantation management. In: Carey WD, ed. Cleveland Clinic: Current Clinical Medicine. 2nd ed. Philadelphia, Pa: Saunders Elsevier; 2010.

Barry JM, Jordan ML, Conlin MJ. Renal transplantation. In: Wein AJ, ed. Campbell-Walsh Urology. 9th ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 40.

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