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Los humectantes que contengan urea, lactato de amonio u otros alfahidroxiácidos pueden servir. Igualmente, se pueden utilizar retinoides, como el tazaroteno, en la piel (uso tópico).
El tratamiento génico para corregir defectos genéticos puede ser posible en el futuro.
Cuando la membrana de colodión se desprende, los bebés están en riesgo de infección.
Más adelante en la vida, se pueden presentar problemas oculares, debido a que los ojos no pueden cerrarse por completo.
Morelli JG. Disorders of keratinization. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF, eds. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 657.
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