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Fisura palatina (hendidura del paladar); Defecto craneofacial
Son defectos congénitos que afectan el labio superior y el paladar.
Existen muchas causas para el labio leporino y el paladar hendido, como problemas con los genes que se transmiten de uno o ambos padres, drogas, virus u otras toxinas que también pueden causar estos defectos congénitos. El labio leporino y el paladar hendido pueden ocurrir junto con otros síndromes o anomalías congénitas.
El labio leporino y el paladar hendido pueden:
Los factores de riesgo son, entre otros, antecedentes familiares de labio leporino o paladar hendido y la presencia de otras anomalías congénitas. Aproximadamente 1 de cada 2,500 personas presenta paladar hendido.
Friedman O, Wang TD, Milczuk HA. Cleft lip and palate. In: Cummings CW, Flint PW, Haughey BH, et al, eds. Otolaryngology: Head & Neck Surgery. 4th ed. Philadelphia, Pa: Mosby Elsevier; 2005:chap 176.
Kliegman RM, Behrman RE, Jenson HB, Stanton BF. Cleft lip and palate. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF, eds. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 307.
Arosarena OA. Cleft lip and palate. Otolaryngol Clin North Am. 2007 Feb;40(1):27-60.
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