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Síndrome de Barrett - Overview

Definición:

Es un trastorno en el cual el revestimiento del esófago (el tubo que lleva el alimento desde la garganta hasta el estómago) presenta daño a causa del ácidos gástrico.

Ver también: enfermedad por reflujo gastroesofágico (ERGE)

Causas:

Cuando usted come, el alimento pasa desde la garganta al estómago a través del esófago (también llamado el conducto del alimento o de la deglución). Una vez que el alimento está en el estómago, un anillo de músculos impide que se devuelva hacia el esófago.

Si estos músculos no se cierran herméticamente, el ácido gástrico puede filtrarse de vuelta hacia el esófago, lo cual se denomina reflujo o reflujo gastroesofágico.

Este reflujo puede causar síntomas de acidez gástrica. También puede dañar el revestimiento del esófago, lo cual se denomina síndrome de Barrett.

El síndrome de Barrett ocurre con más frecuencia en hombres que en mujeres. Usted es más propenso a tener esta afección si ha tenido ERGE durante mucho tiempo.

Los pacientes con síndrome de Barrett pueden desarrollar más cambios en el esófago denominados displasia. Cuando la displasia está presente, se incrementa el riesgo de desarrollar cáncer esofágico.

  • Reviewed last on: 8/1/2009
  • George F. Longstreth, MD, Department of Gastroenterology, Kaiser Permanente Medical Care Program, San Diego, California. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Wilson JF. In the clinic. Gastroesophageal reflux disease. Ann Intern Med. 2008;149:ITC2-1-ITC15; quiz ITC2-16.

Wang, KK and Sampliner RE. Updated guidelines 2008 for the diagnosis, surveillance and therapy of Barrett's esophagus. Am J Gastroenterol. 2008;103:788-797.

Shaheen NJ, Sharma P, Overholt BF, Wolfsen HC, Sampliner RE, Wang KK, et al. Radiofrequency ablation in Barrett's esophagus with dysplasia. N Engl J Med. 2009;360:2277-2288.

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