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Sobreproducción ovárica de andrógenos - Symptom

Síntomas:

Hiperandrogenismo:

Acné
Amenorrea (ausencia de períodos menstruales)
Cambios en el contorno corporal femenino
Disminución del tamaño de las mamas
Aumento del vello corporal en un patrón masculino (hirsutismo), como por ejemplo en la cara, el mentón y el abdomen
Piel grasosa

Virilización:

Clitoromegalia (agrandamiento del clítoris)
Engrosamiento de la voz
Incremento en la masa muscular
Calvicie temporal (adelgazamiento y pérdida del cabello)

Signos y exámenes:

El médico llevará a cabo un examen físico. Cualquier examen de sangre o imagenológico dependerá de los síntomas específicos, pero puede incluir:

Examen de 17-hidroxiprogesterona
Examen de corticotropina
Tomografía computarizada
Examen de sangre para deshidroepiandrosterona
Examen de glucosa
Examen de insulina
Ecografía de la pelvis
Examen de prolactina (si los períodos son infrecuentes o ausentes)
Examen de testosterona
Examen de colesterol total
Examen de hormona estimulante de la tiroides (si hay calvicie)

Sobreproducción ovárica

Desarrollo del folículo

Reviewed last on: 6/7/2010
Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington, School of Medicine; Susan Storck, MD, FACOG, Chief, Eastside Department of Obstetrics and Gynecology, Group Health Cooperative of Puget Sound, Redmond, Washington; Clinical Teaching Faculty, Department of Obstetrics and Gynecology, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Lobo RA. Hyperandrogenism: physiology, etiology, differential diagnosis, management. In: Katz V, Lobo RA, Lentz G, Gershenson D, eds. Comprehensive Gynecology. 5th ed. Philadelphia, Pa: Mosby Elsevier; 2007:chap 40.

Bulun SE, Adashi EY. The physiology and pathology of the female reproductive axis. In: Kronenberg HM, Melmed S, Polonsky KS, Larsen PR, eds. Williams Textbook of Endocrinology. 11th ed. Philadelphia, Pa: Saunders Elsevier; 2008:chap 16.

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