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Agranulocitosis - All Information

Nombres alternativos

Granulocitopenia; Granulopenia

Definición:

Es una insuficiencia de la médula ósea para producir suficientes glóbulos blancos (neutrófilos). La médula ósea es el tejido blando dentro de los huesos que ayuda a formar células sanguíneas.

Causas, incidencia y factores de riesgo:

La agranulocitosis puede ser causada por:

  • Ciertas enfermedades de la médula ósea como mielodisplasia
  • Quimioterapia y trasplante de médula ósea

La agranulocitosis provoca que una persona no tenga suficiente cantidad de un tipo específico de glóbulos blancos, llamados neutrófilos o granulocitos. Un conteo de neutrófilos bajo (neutropenia) también puede ocurrir cuando los glóbulos blancos son destruidos en forma más rápida de lo que pueden ser producidos.

Síntomas:

Las personas con esta afección son más propensas a desarrollar infecciones.

Signos y exámenes:

Ver: examen de fórmula leucocitaria

  • Reviewed last on: 9/6/2010
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; James R. Mason, MD, Oncologist, Director, Blood and Marrow Transplantation Program and Stem Cell Processing Lab, Scripps Clinic, Torrey Pines, California. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Bagby GC. Leukopenia and leukocytosis. In Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007: chap 173.

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