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Hipertermia maligna
Definición:
Es una enfermedad hereditaria que ocasiona una rápida elevación de la temperatura corporal ( fiebre ) y contracciones musculares intensas cuando la persona afectada recibe anestesia general.
Esta afección no es lo mismo que hipertermia debido a emergencias médicas, tales como insolación .
Nombres alternativos:
Hiperpirexia maligna; Hipertermia de tipo maligno
Causas, incidencia y factores de riesgo:
La hipertermia maligna es un rasgo autosómico dominante, lo que quiere decir que sólo se requiere un padre portador de la enfermedad para que el hijo la herede, y puede estar asociada con enfermedades musculares como miopatÃa de multi y minicuerpos centrales y miopatÃa de cuerpos centrales.
Una forma de hipertermia maligna es causada por un defecto en el gen receptor de rianodina (RYR1).
Referencias:
Marx J. Rosen’s Emergency Medicine: Concepts and Clinical Practice . 5th ed. St. Louis, Mo: Mosby; 2002:2000.
- Fecha de revisión: 7/25/2007
- Versión en inglés revisada por: Chad Haldeman-Englert, MD, Division of Human Genetics, Children's Hospitalof Philadelphia, Philadelphia, PA. Review provided by VeriMed HealthcareNetwork.
- Traducción y localización realizada por: DrTango, Inc.
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