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Degeneración hepatocerebral - Overview

Nombres alternativos

Degeneración hepatocerebral crónica adquirida (no Wilsoniana)

Definición:

Es un trastorno cerebral que ocurre en personas con daño hepático.

Causas, incidencia y factores de riesgo:

Esta afección puede presentarse en cualquier caso de insuficiencia hepática adquirida, incluyendo hepatitis severa.

El daño hepático puede llevar a la acumulación de amoníaco y otros materiales tóxicos en el cuerpo. Esto sucede cuando el hígado no funciona adecuadamente para descomponer y eliminar estos químicos. Los materiales tóxicos pueden dañar el tejido cerebral.

Las áreas específicas del cerebro, como los ganglios basales que ayudan a controlar el movimiento, son más susceptibles a presentar daño a causa de la insuficiencia hepática. Esta afección es del tipo "no wilsoniana". Esto significa que el daño hepático no es causado por depósitos de cobre en el hígado, que es un rasgo clave de la enfermedad de Wilson.

  • Reviewed last on: 7/7/2010
  • David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; George F. Longstreth, MD, Department of Gastroenterology, Kaiser Permanente Medical Care Program, San Diego, California. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Garcia-Tiso G. Cirrhosis and its sequellae. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 157.

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