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Deficiencia selectiva de lgA - Overview

Nombres alternativos

Deficiencia de IgA

Definición:

Es el trastorno de inmunodeficiencia más común. Las personas con este trastorno presentan ausencia o bajos niveles de una proteína sanguínea llamada inmunoglobulina A.

Causas, incidencia y factores de riesgo:

La deficiencia de lgA generalmente es hereditaria, lo que significa que se transmite de padres a hijos. Sin embargo, se ha informado de casos de deficiencia de IgA inducida por fármacos.

Se puede heredar como un rasgo autosómico dominante o autosómico recesivo. Este trastorno se encuentra en aproximadamente 1 de cada 700 personas de origen europeo y es menos común en personas de otros grupos étnicos.

Ver también: celiaquía

Anticuerpos

Reviewed last on: 5/16/2010
David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Stuart I. Henochowicz, MD, FACP, Associate Clinical Professor of Medicine, Division of Allergy, Immunology, and Rheumatology, Georgetown University Medical School. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

Referencias

Azar AE. Evaluation of the adult with suspected immunodeficiency. Am J Med. 2007;120(9):764-768.

Ballow M. Primary immunodeficiency diseases. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 271.

Morimoto Y. Immunodeficiency overview. Prim Care. 2008;35(1):159-157.

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